Root Mean Square of the Successive Differences (RMSSD) is one of a few time-domain tools used to assess heart rate variability, the successive differences being neighboring RR intervals. The automated analysis routine in AcqKnowledge® will perform the analysis within fixed time intervals, between event boundaries (user defined event marks), and focus areas within the data. The software will either paste the data into a journal file or a spreadsheet for further analysis.
Use AcqKnowledge‘s Multi-epoch HRV – Statistical analysis routine to automate RMSSD, SDSD, and pNN50 HRV calculations. There is also an additional script option to perform the same analysis – Script 056: Compute HRV Statistics.
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Figure 1 R-R interval
Figure 1 shows the R-R intervals labeled A = (R-R)1, B = (R-R)2, C = (R-R)3, …. (R-R)i represents the interval between two neighboring QRS peaks.
The RMSSD is looking for the successive difference between the intervals meaning:
A-B à(R-R)1 – (R-R)2
B-C à(R-R)2 – (R-R)3…and so forth
The RMSSD calculates to:
RMSSD =
where N = number of RR interval terms
Using the option to export the HRV tachogram to Excel, the calculation of the RMSSD is structured in Excel to appear as shown in Figure 2:
Figure 2 Excel sheet for RMSSD calculation
BIOPAC Research Solutions | ECG
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MP36R System
Wired | RMSSD for HRV Analysis
MP36R with AcqKnowledge plus lead set & long-term recording electrodes
MP36R System
Wired | RMSSD for HRV Analysis
MP36R with AcqKnowledge plus electrode lead adapter, adhesive disks, 8 mm shielded & unshielded TP electrodes
MP160 System
Wired | RMSSD for HRV Analysis
MP160 plus AcqKnowledge with three ECG amps, multi-lead egg cable, and long term electrodes
MP160 System
Wired | RMSSD for HRV Analysis
MP160 plus AcqKnowledge with ECG amp, module extension cable and long-term electrodes
MP36R System
MP36R System
MP160 System
MP160 System
Mobita
Wireless | RMSSD for HRV Analysis
Mobita system for up to 32-CH Wireless Biopotentials plus AcqKnowledge
Mobita
MP160 System
MRI | RMSSD for HRV Analysis
MP160 plus AcqKnowledge with ECG MRI amp, MRI cable/filter system to biopotential amps, disposable radiotranslucent electrodes and electrode gel
MP160 System
MP36R System
Animal | RMSSD for HRV Analysis
MP36R with AcqKnowledge plus electrode lead adapter and three 12 mm TP unipolar needle electrodes
Stellar
Animal | RMSSD for HRV Analysis
Schedule, Record, and Analyze Stellar Telemetry Data with AcqKnowledge
MP160 System
Animal | RMSSD for HRV Analysis
MP160 plus AcqKnowledge with ECG amp, module extension cable, and unipolar needle electrodes
MP36R System
Stellar
MP160 System
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