Monophasic Action Potential

Use the MCE100C amplifier module to record the MAP signal and use the Macintosh version of AcqKnowledge to automate the analysis process. The software performs classification of MAP data acquired from a human or animal subject and extracts various cycle by cycle intervals. The software scores the waveform to identify the appropriate points of the signal, measures the data, plots the results and exports them to a spreadsheet. Locates upstroke, maximum, 100% recovery, and user-specified recovery points on the action potential.

  • Classification is performed using the action potential with its smoothed derivative; pre-filtering noise with lowpass filters may improve classification.
  • If upstroke, maximum, and plateau events are already defined on the MAP signal, the classifier is not invoked and only recovery events are defined.
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The analysis outputs the following information on a cycle-by-cycle basis and the textual output cites the average of all of the cycle-by-cycle values:

Name Abbrev.
100% recovery period 100% REC
dV/dt Maximum dV Max
dV/dt Minimum dV Min
End diastolic voltage EDV
Maximum voltage MAX
Minimum voltage MIN
Plateau voltage PLAT
Rate
Stroke amplitude AMP
User recovery period % REC

 

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