Calculate and record left ventricular pressure (LVP) data from acute, chronic and isolated heart preparations. Use the MPMS200 Micro Pressure Measurement System for small vessel recordings, including mouse left and right ventricular blood pressure. Interface with a variety of invasive transducers, including the popular series of Millar Mikro-Tip Catheters.
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AcqKnowledge® extracts various cycle-by-cycle cardiac measures of left ventricular blood pressure data, optionally in conjunction with an ECG Lead II signal. Define events at the systolic pressure and the left ventricular end diastolic pressure (LVEDP) for each cycle; examine the LVP signal and its derivative. Selected preferred location method—Adaptive threshold of 0 plus a percentage of the peak to peak change in pressure OR First zero crossings before contraction. Examines the LVP signal, ECG, and derivative of the LVP signal.
The analysis outputs the following information on a cycle-by-cycle basis and the textual output cites the average of all of these cycle-by-cycle measurements:
| Name | Abbrev. |
| Contractility index | CI |
| Developed pressure | DP |
| dP/dt Max | – |
| dP/dt Min | – |
| End diastolic pressure | LVEDP |
| Minimum pressure | Min |
| QA Interval | QA |
| Rate | – |
| Recovery time | %REC |
| Systolic pressure | SYS |
| TAU | |
| Tension time index | TTI |
Long-term wireless ECG system Wireless ECG implantable transmitters for mice or rats Additional transmitters available—just move the receiver tray to record from multiple home cages The Epoch ECG Transmitter amplifies and transmits high-fidelity ECG data. Implants are small enough to be implanted into mice as young as P18. To record, simply place the animal’s cage on top of the […]
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