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Regional Blood Flow

To analyze regional blood flow, occlude the venous return with the blood pressure cuff (TSD120) and measure the swelling of the distal portion of the limb with a mercury strain gauge, otherwise known as a strain gauge plethysmograph (SPG). This Pneumo Plethysmography (PnuPG) test allows users to monitor changes from a baseline reading and compare responses from one subject to the next. Typically, the initial slope of the response is determined, and a series of measurements are taken, including:

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BIOPAC applications and life science data analysis
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  • Venous capacitance—The inflow curve plateaus because eventually the venous pressure rises sufficiently to force blood past the occluding cuff; the increased volume at this point thus represents the capacity of the venous system to store blood and is termed the venous capacitance.
  • Venous outflow—Use venous outflow to determine deep venous thrombosis (DVT). Rapidly release the cuff pressure from the point of maximum swelling and record the time taken for the signal to return to the normal (pre-inflation) level. The level of flow resistance determines the time it takes the flow signal to return to normal.
  • Venous compliance—To measure venous capacitance as a function of pressure, follow the procedure for measuring venous capacitance but use different occluding cuff pressures. The slope of this relationship measures the venous compliance.

The mercury strain gauge interfaces with the DA100C amplifier and a TCI111A/112.

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