Pulse Transit Time (PTT) is the time it takes the Pulse Pressure (PP) waveform to propagate through a length of the arterial tree. The pulse pressure waveform results from the ejection of blood from the left ventricle and moves with a velocity much greater than the forward movement of the blood itself. To measure pulse transit time, record the onset of the R-wave with an ECG100C amplifier and record the pulse waveform at the fingertip using a TSD200 and the PPG100C amplifier or wirelessly with BioNomadix. Use AcqKnowledge to determine the cyclic peak time of both waveforms, then subtract the ECG R-wave peak time from the PPG peak time.
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To calculate Pulse Wave Velocity (PWV) , first measure the distance from the heart to the location of the TSD200 sensor, then divide the distance by the PTT. PWV is related to blood pressure delta (Systsolic – Diastolic) in accordance with the following equation (from Bramwell & Hill, 1922):
PWV = K Sqrt [V (Pd/Vd)]
AcqKnowledge software can also measure the Pulse Wave Amplitude (PWA) or Pulse Pressure (PP) on a cycle-by-cycle basis by using the Rate function. The Rate function will identify each pulse waveform and measure the amplitude of the signal and report the result as a new channel. The Rate function is available for on-line and off-line analysis of the pulse waveform.
Record pulse data wirelessly with BioNomadix or with standard wired amplifiers and use calculation channels and the find cycle/peak automated analysis routine in AcqKnowledge to easily calculate and extract pulse transit time and pulse wave velocity values. Results can be displayed as graph channels and the PTT and PWV values can be exported to a spreadsheet for further statistical analysis.
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MP36R System
Wired | Pulse Transit Time (PTT), Pulse Wave Velocity (PWV) and Pulse Wave Amplitude (PWA)
MP36R with AcqKnowledge plus lead set, PPG transducer, disposable general purpose electrodes & gel
MP36R System
Wired | Pulse Transit Time (PTT), Pulse Wave Velocity (PWV) and Pulse Wave Amplitude (PWA)
MP36R with AcqKnowledge plus PPG transducer, electrode lead adapter, 8 mm shielded & unshielded TP electrodes
MP160 System
Wired | Pulse Transit Time (PTT), Pulse Wave Velocity (PWV) and Pulse Wave Amplitude (PWA)
MP160 System with PPG and ECG amplifier, finger transducer and disposable electrodes
MP36R System
MP36R System
MP160 System
MP160 System
Wireless | Pulse Transit Time (PTT), Pulse Wave Velocity (PWV) and Pulse Wave Amplitude (PWA)
MP160 plus AcqKnowledge with wireless PPG/EDA and ECG amps, pulse transducer and general purpose electrodes
BioNomadix Logger
Wireless | Pulse Transit Time (PTT), Pulse Wave Velocity (PWV) and Pulse Wave Amplitude (PWA)
BioNomadix Logger and two transmitters for wireless PPG/EDA and ECG plus Pulse transducer, leads & electrodes
MP160 System
BioNomadix Logger
MP160 System
MRI | Pulse Transit Time (PTT), Pulse Wave Velocity (PWV) and Pulse Wave Amplitude (PWA)
MP160 System with PPG and ECG amplifier, finger transducer, and disposable electrodes for MRI
MP160 System
MP36R System
Animal | Pulse Transit Time (PTT), Pulse Wave Velocity (PWV) and Pulse Wave Amplitude (PWA)
MP36R with AcqKnowledge plus PPG transducer, electrode lead adapter and 12 mm TP unipolar needle electrodes
MP160 System
Animal | Pulse Transit Time (PTT), Pulse Wave Velocity (PWV) and Pulse Wave Amplitude (PWA)
MP160 System with PPG and ECG amplifier, transducer and needle electrodes
MP36R System
MP160 System
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