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Auditory Brainstem Response (ABR)

MP Devices can be used for a wide variety of Brainstem Evoked Potential (BEP), Brainstem Evoked Response (BER), Brainstem Auditory Evoked Potential (BAEP), Brainstem Auditory Evoked Response (BAER), Brainstem Evoked Response Audiometry, and Brainstem Evoked Response (BSER) tests. The MP device is capable of delivering auditory stimulation and recording and averaging the response data. The system can also interface with a wide variety of stimulus presentation systems to deliver auditory waveforms and the averaging mode can handle oddball paradigms for Middle Latency Auditory Evoked Potential (MAEP) and Auditory Middle Latency Response (MLR) tests. The averaging window can be adjusted to include the time period of interest for the particular response being studied.

For ABR studies the STM100C Stimulator module should interface with the OUT101 Ear Tubephone to deliver clicks and tones to the subject. Use the ERS100C to record the evoked response from the subject and set AcqKnowledge to average the signal.

 

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Record neuro-physiological responses along the auditory pathway resulting from auditory stimulation. When performing an ABR, using the MP150, it’s usually best to record at least two channels of data. One channel is the output from the ERS100C amplifier connected to the subject and the other channel is the stimulus level which drives the OUT101 Tubephone or other auditory stimulator.

Latency values, which are not possible to achieve, are reflected as an adjustment message (generated by the AcqKnowledge software) when the acquisition is first performed. The message informs the user as to the options to continue with the acquisition, given the acquisition parameters. If the specified Latency is possible, then the adjustment message will not appear and the acquisition will start automatically when the START button is pressed.

The fastest repetition rate (smallest latency between clicks) will be a function of the following variables:

1) Acquisition Length: the longer the length, the higher the latency
2) Sampling Rate: the higher the sampling rate, the higher the latency
3) Number of Channels: the higher the number of recorded and averaged channels,
the higher the latency
4) Speed of Computer: the slower the computer speed, the higher the latency

Calibration for Auditory Brainstem Response Studies

To calibrate the OUT101 Tubephone, use an Etymotic ER-7C Probe Microphone—this microphone provides a calibrated output voltage which is a function of applied Sound Pressure Level (SPL). The sensitivity is 50 mV/Pascal (-46 dB re: 1 V/uBar): 0 dB SPL = 0 dBuV.

Place the Probe Microphone insert tube in the auditory canal prior to the insertion of the OUT101 foam tip. The OUT101 Tubephone sound delivery tube and the Probe Microphone sound input tube will then be exposed to the same auditory chamber. Accordingly, the SPL is recorded, via the Probe Microphone, simultaneously with applied auditory stimulus from the OUT101 Tubephone.

See also

 105c – ABR Calibration for MP150 with AcqKnowledge 4.1       249 – Online Averaging Latency Parameters

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