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MER: Micro-electrode Recording

Advanced Tools for Microelectrode Recording & Data Analysis

Record signals from a wide range of micro-electrodes on organisms, organs, tissues, brain slices & cells

Flexible interface with options for driven or grounded shields, negative capacity generation and current clamping

microelectrode recording apps

Record & Analyze Potentials

Now researchers have access to powerful BIOPAC hardware and software combinations that allow them to record signals from a wide range of micro-electrodes on organisms, organs, tissues, brain slices, and cells. Researchers can use up to 16 MCE100C amplifiers simultaneously to record in-vivo or in-vitro signals. The MCE100C has a very flexible interface (with options for a driven or grounded shields, negative capacity generation and current clamping) to customize electrodes for the recording environment. Analyze potentials using a variety of methodologies (e.g., perform time series analysis, FFT analysis, or histogram the data for amplitude or time values). Examine data from channel to channel for timing measurements or morphological comparisons.

Try MER tools in the free AcqKnowledge Demo

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General micro-electrode signal amplification

Designed to work with a wide range of micro-electrodes in a variety of measurement applications

Current Clamping

Integral current clamp feature controlled via an applied voltage signal

Cell Transport/Ussing Chamber Measurements

Using AcqKnowledge, standard or arbitrary current wave shapes can be output (up to 100nA) using the MCE100C

Application Starter Hardware  

Hardware Packages   |   MER: Micro-electrode Recording

Hardware Bundles are complete solutions for the specified application. Choose your preferred platform and bundle, then click "Request Pricing" to request an estimate, add/remove items, or complete purchase. If you have questions about specific items, click through to the product web page for details and specifications, or contact your Local Sales contact.

Wired

Animal

Details

Available BIOPAC Micro-Electrode solutions include:

  • MCE100C: high input impedance, low noise, differential amplifier
  • MCEKITC: interface kit to build your own customized adapter

AcqKnowledge® provides powerful options for analysis, control, display, and stimulation. The software includes a range of tools and automated analysis routines for many laboratory applications. The tools include:

• Stimulation: AcqKnowledge® includes stimulation control software that interfaces with BIOPAC’s range of constant current and constant voltage stimulators. The software can delivery square, ramp, sine and arbitrary waveforms  for a wide range of stimulus paradigms.

• Spike Analysis: The Neurophysiology analysis suite includes a number of tools for the identification of spikes within extracellular data. The software will identify the spike using a fixed threshold crossing method using a user defined multiple of the standard deviation to the mean signal. The data is scored by placing event marks that identify the onset and offset of the spike. The software provides options for histogramming the data based on spike amplitude or dwell time. A spike train generation utility identifies when action potentials are firing. The spike events are also used to synchronize averaging of the average action potential. A spike classification feature uses a K-means clustering algorithm to group the spikes into unique classes for sorting. There is also a tool for identifying overlapping spike episodes.

Ion-Selective Micro-Electrode Interface: Use ion-specific electrodes to monitor the change in a preparation’s ion concentration. To determine ionic activity, use the Equation Generator in AcqKnowledge to implement the Nernst equation.

Advanced Features Spotlight

AcqKnowledge expression dialog

Ion-Selective Micro-electrode Interfacing

To perform potentiometric measurements using electrochemical cells, record voltages with nearly zero current flow. Use ion-specific electrodes to isolate a change in the respective ion concentration More...

Iontophoresis

Iontophoresis is a method of inducing ionic drug solutions to pass into tissue by the application of a small electrical current. Use the MCE100C to inject More...

Tissue Conductance Measurement

Tissue conductance measurements can be performed with the MCE100C using either AC or DC excitation currents. Use surface, needle or micro-electrodes to interface to the More...

General Micro-Electrode Signal Amplification

The MCE100C micro-electrode amplifier is designed to work with a wide range of micro-electrodes in a variety of measurement applications. To record biopotentials, use standard More...

Cell Transport/Ussing Chamber Measurements

For certain applications, the MCE100C can perform cell transport measurements. Typically, these applications require the use of a small current applied through a pair of More...

Support

Application Notes

Knowledge Base

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