On Demand | A New Bioimpedance Technique: Indexing Dynamic Activity of the SNS

Watch this online seminar to learn more about Bioimpedance and more specifically, Trans-radial Electrical Bioimpedance Velocimetry (TREV). The TREV technique can record important cardiovascular data such as Contractility Index, Acceleration, Velocity, Integral of Velocity, and Cardiac Output. Researchers describe how they have used this technology in their research projects to record the Contractility Index as a robust measure of dynamic sympathetic nervous system activity. The researchers describe their experimental setup, data collection techniques for in lab and MRI, and analysis methodology.

The TREV technique measures beat-by-beat cardiac contractility with less of the complications associated with transthoracic impedance cardiography. BIOPAC has developed special hardware to reduce setup time and complexity as well as obtain high-quality data without the subjectivity of locating the B-point (aortic valve opening time). They discuss their use of the TREV technique and the data they collected using it.

Traditional transthoracic bioimpedance uses either tape, strip, or spot electrodes placed around, or on, the sides of the torso. It takes considerable time to set up the participant and the technique is overly sensitive to upper body movement, requiring special care and instructions for participants to limit these movements. There is a trade-off between participant comfort and data quality, and this can also influence the ecological validity of the study.

With transthoracic impedance cardiography, normal breathing causes changes of thoracic shape that are not accounted for in ideal models used to calculate cardiovascular measures. The heart’s venous return complicates the problem of examining sympathetic responses separately from other physiological variables. In addition, the analysis depends on locating the B-point (aortic valve opening time). This point can be difficult to identify, even when experts are involved.

TREV avoids many of the transthoracic issues by placing electrodes on the forearm of the participant, minimizing setup time, and avoiding the upper body motion and ventilation issues associated with transthoracic impedance cardiography.

Topics Covered:

  • Presentation and discussion of TREV
  • Presentation and discussion of research applications
  • Hardware setup
  • Participant setup
  • Review of results from other tests

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