MER: Micro-electrode Recording

Modular construction...extreme flexibility

MP systems offer features to support nearly every physiological recording scenario. The following advanced features apply to the application you selected.

If you don't see an Advanced Feature that interests you, please contact BIOPAC so we can identify the best solution for your particular need.

Cell Transport/Ussing Chamber Measurements

For certain applications, the MCE100C can perform cell transport measurements. Typically, these applications require the use of a small current applied through a pair of electrodes. By monitoring the voltage change across the electrodes it’s possible to assess aspects of cellular motility. Using AcqKnowledge, standard or arbitrary current (up to 100nA) wave shapes can be […]

General Micro-Electrode Signal Amplification

The MCE100C micro-electrode amplifier is designed to work with a wide range of micro-electrodes in a variety of measurement applications. To record biopotentials, use standard reusable or disposable Ag-AgCl electrodes or needle electrodes. For cellular measurements, interface the MCE100C with etched metal electrodes, micropipette and metal film-coated electrodes. The MCE100C can be configured to support […]

Hardware Flexibility

Use the MCEKITC to interface a variety of micro-electrode cables to the MCE100C amplifier. For your pre-existing setup, choose an appropriate Analog Connection Cable to connect your microelectrode amplifier to the MP System.

Ion-Selective Micro-electrode Interfacing

To perform potentiometric measurements using electrochemical cells, record voltages with nearly zero current flow. Use ion-specific electrodes to isolate a change in the respective ion concentration in the test solution. To determine ionic activity, use the Equation Generator in AcqKnowledge to implement the Nernst equation.

Iontophoresis

Iontophoresis is a method of inducing ionic drug solutions to pass into tissue by the application of a small electrical current. Use the MCE100C to inject precise amounts of current (up to 100nA) into the tissue during signal acquisition; use the recording electrodes or a separate stimulating electrode to inject the current. To specify the shape, […]

Single Channel Analysis

Use the amplitude histogram function in AcqKnowledge to inspect the raw data from a single ion channel to determine if multiple channels are present, and use the threshold function to create an events list from the raw single channel data. Apply the rate detector to the events list to determine individual event area (duration) and […]

Tissue Conductance Measurement

Tissue conductance measurements can be performed with the MCE100C using either AC or DC excitation currents. Use surface, needle or micro-electrodes to interface to the tissue. Use four electrodes to perform standard tetrapolar measurements-two to drive current and two to monitor voltage.