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Noninvasive Cardiac Output Module

The NICO100C Impedance Cardiography (ICG) Noninvasive Cardiac Output Module records specific parameters associated with cardiac output measurements. It incorporates a precision high frequency current source, which injects a very small (400 µA) measurement current through the thoracic volume defined by the placement of a set of current source electrodes. A separate set of monitoring electrodes measures the voltage developed across the thorax volume. Because the current is constant, the voltage measured is proportional to the impedance characteristics of the thorax.

The NICO100C simultaneously measures impedance magnitude (Zo; labeled "Z") and derivative (dZ/dt; labeled "DZ"). Zo and dZ/dt can be recorded at four different measurement frequencies, from 12.5kHz to 100kHz; cardiac output measurements are usually performed at a measurement frequency of 50 kHz.

AcqKnowledge includes automated tools for the automatic analysis of impedance cardiography (ICG), cardiac output and other hemodynamic parameters using noninvasive bioimpedance techniques. The software automatically scores the data and provides tabulated results in either a Journal file or Excel. Click below for ICG Analysis video...

Output Channels
The CH SELECT switch has four bank settings, which assign NICO100C output (Zo and dZ/dt) channels as follows:

Bank Magnitude (Zo) Derivative (dZ/dt)
1 Channel 1 Channel 9
2 Channel 2 Channel 10
3 Channel 3 Channel 11
4 Channel 4 Channel 12

If a particular NICO100C output is not used, the respective assigned channel cannot be used for another modules output; simply do not record on the assigned channel.

Possible Lead Configurations

  • Human, Absolute, Shielded: LEAD130 lead with EL506 bioimpedance strip or EL500 paired disposable electrodes.
  • Human, Absolute, Unshielded: 8 x LEAD110 leads with 4 x CBL204 Touchproof "Y" lead adapters and EL500 paired disposable electrodes.
  • Human, Relative Measures, Unshielded or Small Animal or EBI-specific Measures (flow, plethysmography, etc.): 4 x LEAD110 leads with EL506 bioimpedance strip or EL500 paired disposable electrodes.
    • Use for injecting current and averaging at four paired-electrode sites (required for cardiac output measurements). The best placement for all eight electrodes, considering the anatomical shape of the thorax, is along the frontal plane (wider dimension). When directed through the thorax, the measurement current seeks the shortest and most conductive pathway. Consequently, the measurement current flows through the thoracic aorta and vena cava superior and inferior.

See also

 Cardiovascular Hemodynamics
     Hardware for human and animals. Measure continuous BP, ECG, stroke volume, cardiac output, PPG, etc. For animal and tissue look at acute and chronic dose-response.
 ICG: Impedance Cardiography/Cardiac Output
     Record cardiac output, thoracic impedance changes, or any kind of bioimpedance signal. Use AcqKnowledge for a fully automated ICG analysis and dZ/dt waveform classifier.
 Neuromarketing and Neuroeconomics
     Neuromarketing and neuroeconomics tools to study consumers' sensorimotor, cognitive, and affective response to marketing stimuli and decision making tasks. Use fNIR, MRI solutions, EEG, and wireless physiology.
 Noninvasive Blood Pressure Monitoring
     Human—continuous system with finger sensor. Fits children through large adults. MRI system also available. Animal—tail cuff sensor with automatic inflation.
     Record and analyze BP, ECG, HRV, EDA, EMG, EEG, EOG, RSP, etc. Interface to stimulus presentation programs...use automated analysis routines to easily score and analyze data.

Knowledge Base Topics
Search the Knowledge Base or Ask a Question if your issue isn't listed here.
 Amplifier conversion - 2 mm to touchproof
 Amplifier filter settings
 Amplifier Module Filter Response Times
 Differences between EBI and NICO modules
 Galvanic Isolation Guidelines for the MP150 System
 Glossary of Specification Terminology
 Grounding guidelines
 Guidelines for Psychophysiological Recordings
 Heart rate from ICG
 High pass filters
 Impedance considerations - EBI100C and NICO100C
 Low pass filters
 Measuring LVET
 Multiple subjects per amplifier or multiple amplifiers per subject
 Notch filter
 Optimal ground placement
 Poincare plot from R-R tachogram
 Railing signal (flatline)
 Recording good data
 Respiration from impedance
 Sample rates for different signals
 Signal drifts to zero
 Single spot electrodes for ICG
 Skin surface area calculation
 Tutorial on Electrostatic Discharge
 Typical impedance cardiography values
 Using BIOPAC research amplifiers with the BSL System
 Zero adjust on NICO100C and EBI100C

MP Systems Hardware Guide
AcqKnowledge 4 Software Guide
MP Research System User List
Application Note: NICO100C and LEAD130 Noninvasive Cardiac Ouput Measures
Product Citations: review publications summary or conduct a search
MP Research Catalog
BioNomadix Wireless Physiology Catalog
New Products Catalog
MRI Catalog
VR and Stimulus Presentation Catalog
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