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General Micro-Electrode Signal Amplification


The MCE100C micro-electrode amplifier is designed to work with a wide range of micro-electrodes in a variety of measurement applications.

To record biopotentials, use standard reusable or disposable Ag-AgCl electrodes or needle electrodes. For cellular measurements, interface the MCE100C with etched metal electrodes, micropipette and metal film-coated electrodes.

The MCE100C can be configured to support a range of electrode signal input compensation requirements.

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This is one of many ADVANCED FEATURES for the selected Application. Scroll down for hardware options.


To maintain a high-frequency amplifier response, two input capacity compensation methods, Driven Shield Compensation and Negative Capacity Generation, can be optionally applied for recording. Employ the compensation methods simultaneously or ground the input shields (to reduce noise) and then apply Negative Capacity compensation to counter the effects of the shield and/or electrode capacitance.

  • Single/Multiple Cell Recording
  • Brain Slices
  • Smooth, Skeletal, Cardiac Muscle
  • Corneal / Retinal Potentials
  • Cortical, Muscle & Nerve Action/Resting Potentials
  • Extra- / Intra-cellular Signal Amplification


Application Notes

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